Article

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis

2019-05-31

Abstract excerpt

Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the development of itch and the acute-to-chronic itch transition remain unknown. Here, we show that skin-infiltrating neutrophils are key initiators of itch in atopic dermatit...

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Literature Corpus work: a34e0320-040f-54c4-97bf-144661695a4d
DOI: 10.1101/653873

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