Article

Dpp and Immune Response Pathways Factors Mediate Paracrine Induction of Senescent Cells in <i>Drosophila</i>

2025-12-14

Abstract excerpt

<h4>Summary</h4> Transition toward senescence is a cellular response to different stressors like ionizing radiation, telomere shortening or oncogene activation. This phenomenon is evolutionarily conserved across species, from insects to humans. Senescent cells (SCs) permanently withdraw from the cell cycle and undergo a series of physiological changes, most notably the acquisition of a robust secretory activity c...

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Literature Corpus work: a34a8d70-589d-52a3-97a4-0a655061bbdc
DOI: 10.64898/2025.12.11.693679

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