Article

Is “Cellular Senescence” a Misnomer?

2022-07-27

Abstract excerpt

One of the most striking findings in biogerontology in the 2010s was the demonstration that elimination of senescent cells delays many late-life diseases and extends lifespan in mice. This implied that accumulation of senescent cells promotes late-life diseases, particularly through action of senescent cell secretions (the senescence-associated secretory phenotype or SASP). But what exactly is a senescent cell? Su...

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Literature Corpus work: 91edf639-e5c1-5cab-ba75-98c3f00684b5
DOI: 10.20944/preprints202207.0423.v1

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