Article

Loss of SARA in Hepatic Stellate Cells Exacerbates Experimental Liver Fibrosis

2026-08-20

Abstract excerpt

<title>Abstract</title> <p> Background and aims: Transforming growth factor-β (TGFβ) signalling is a central driver of hepatic fibrogenesis, yet the role of the Smad adaptor protein SMAD Anchor for Receptor Activation (SARA) in hepatic stellate cell (HSC) activation remains unknown. We investigated whether SARA regulates HSC activation and fibrosis progression during chronic liver injury. <h4>Methods:</h4> We as...

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Literature Corpus work: a31b8581-2473-59f1-98b0-096b8d708c44
DOI: 10.21203/rs.3.rs-10662146/v1

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