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SOLAR Mediates Lysosomal Membrane Repair and Redox Defense

2026-07-09

Abstract excerpt

Lysosomal damage is increasingly recognized as a hallmark of aging. Understanding lysosomal quality control may open new therapeutic strategies to enhance lysosomal resilience. Here, we identify SOLAR ( S QSTM1/p62 O ligomer-mediated L ysosomal A ntioxidant Defense And Membrane R epair), a lysosomal quality control pathway that links CASM (conjugation of ATG8 to single membranes) to p62-driven membrane repair...

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Literature Corpus work
a2fb2671-959e-5c61-9816-5db72da3c434
DOI
10.64898/2026.07.08.736954
Open publication

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SOLAR Mediates Lysosomal Membrane Repair and Redox DefenseDOI 10.64898/2026.07.08.736954
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