Article

Deciphering the tissue-specific regulatory role of intronless genes across cancers

2022-02-22

Abstract excerpt

I ntronless genes (IGs) or single-exon genes lacking an intron are found across most Eukaryotes. Notably, IGs display a higher transcriptional fidelity as they are not regulated through alternative splicing, suggesting better predictability biomarkers and easier regulation as targets for therapy. Cancer is a complex disease that relies on progressive uncontrolled cell division linked with multiple dysfunctional b...

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Literature Corpus work: a2f46524-8a89-55b4-8c7d-0e1555d0532f
DOI: 10.1101/2022.02.21.481319

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