Article

Pan-Cancer Profiling of Intron Retention and Its Clinical Significance in Diagnosis and Prognosis

2023-08-30

Abstract excerpt

Alternative splicing can produce transcripts that affect cancer development and shows potential for cancer diagnosis and treatment. However, intron retention (IR), a type of alternative splicing, has been less systematically studied in cancer biology research. Here, we generated a pan-cancer IR landscape for more than 10,000 samples across 33 cancer types from The Cancer Genome Atlas (TCGA). We characterized diffe...

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Literature Corpus work: bf2b218f-3b3b-510f-a31d-a71f215739c6
DOI: 10.20944/preprints202308.2025.v1

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