Article

ELITE: Expression deconvoLution using lInear optimizaTion in bulk transcriptomics mixturEs

2023-03-07

Abstract excerpt

Understanding the cellular composition of tissue samples is crucial for identifying the molecular mechanisms underlying diseases and developing cellular targets for therapeutic interventions. Digital cytometry methods have been developed to predict tissue composition from bulk transcriptomic data, avoiding the high cost associated with single-cell profiling. Here, we present ELITE, a new digital cytometry method t...

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Literature Corpus work: a2d8ef84-67fd-5f8d-8fc5-9ffada28760a
DOI: 10.1101/2023.03.06.531002

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