Article

Deconvolution of omics data in Python with Deconomix – cellular compositions, cell-type specific gene regulation, and background contributions

2024-12-03

Abstract excerpt

<h4>Summary</h4> Gene expression profiles of heterogeneous bulk samples contain signals from multiple cell populations. Studying variations in their composition can help to identify cell populations relevant for disease. Moreover, analyses, such as the identification of differentially expressed genes, can be confounded by cellular composition, as differences in gene expression may arise from both variations in ce...

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Literature Corpus work: 979276ad-7a50-51e5-b7d3-767efa6cad3f
DOI: 10.1101/2024.11.28.625894

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