Article

AutoGeneS: Automatic gene selection using multi-objective optimization for RNA-seq deconvolution

2020-02-23

Abstract excerpt

Tissues are complex systems of interacting cell types. Knowing cell-type proportions in a tissue is very important to identify which cells or cell types are targeted by a disease or perturbation. When measuring such responses using RNA-seq, bulk RNA-seq masks cellular heterogeneity. Hence, several computational methods have been proposed to infer cell-type proportions from bulk RNA samples. Their performance with...

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Literature Corpus work: 6a37bd61-24e1-5199-9f4f-0fa00f485fc8
DOI: 10.1101/2020.02.21.940650

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