Article

Label-free three-photon imaging of intact human cerebral organoids: tracking early events in brain development and deficits in Rett Syndrome

2022-03-01

Abstract excerpt

<h4>ABSTRACT</h4> Human cerebral organoids are unique in their development of progenitor-rich zones akin to ventricular zones from which neuronal progenitors differentiate and migrate radially. Analyses of cerebral organoids thus far have been performed in sectioned tissue or in superficial layers due to their high scattering properties. Here, we demonstrate label-free three-photon imaging of whole, uncleared int...

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Literature Corpus work: a2d636fc-db26-5df9-aea3-09f5618502aa
DOI: 10.1101/2022.02.28.482282

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