Article

Electroporation-Based Gene Delivery and Whole-Organoid Imaging in Human Retinal Organoids

2025-06-11

Abstract excerpt

<h4>Summary</h4> Human retinal organoids (hRetOrg) derived from human induced pluripotent stem cells (hiPSCs) have emerged as powerful in vitro systems for studying retinal development, modeling retinal diseases, and evaluating therapeutic strategies. However, current genetic manipulation approaches, such as stable hiPSC line generation and viral transduction, are laborious, costly, and inefficient, with limited...

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Literature Corpus work: 9f80fc1b-ae6b-5e18-9a10-4eaa2858b7ae
DOI: 10.1101/2025.06.07.658463

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