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Article

SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells

2022-02-22

Abstract excerpt

High expression of the tyrosine kinase FER is an independent prognostic factor that correlates with poor survival in breast cancer patients. To investigate whether the kinase activity is essential for FER oncogenic properties, we developed an ATP analogue-sensitive knock-in allele (FER ASKI ). Specific FER kinase inhibition in MDA-MD-231 cells reduces migration, invasion, and metastasis in a mouse model of breast...

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Literature Corpus work
a2a87058-f7f1-5040-9fb8-38599e8f0c35
DOI
10.1101/2022.02.22.481420
Open publication

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SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cellsDOI 10.1101/2022.02.22.481420
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