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The Role of microRNAs in Alzheimer’s Disease and Their Therapeutic Potentials

21 Mar 2018

Abstract excerpt

MicroRNAs (miRNAs) are short, endogenous, non-coding RNAs that post-transcriptionally regulate gene expression by base pairing with mRNA targets. Altered miRNA expression profiles have been observed in several diseases, including neurodegeneration. Multiple studies have reported altered expressions of miRNAs in the brains of individuals with Alzheimer's disease (AD) as compared to those of healthy elderly adults....

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PMID: 29561798
DOI: 10.3390/genes9040174

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