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Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction

2023-03-06

Abstract excerpt

Macrophage immune checkpoint inhibitors, such as anti-CD47 antibodies, show promise in clinical trials for solid and hematologic malignancies. However, the best strategies to use these therapies remain unknown and ongoing studies suggest they may be most effective when used in combination with other anticancer agents. Here, we developed a novel screening platform to identify drugs that render lung cancer cells mor...

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Literature Corpus work
a22a7205-2856-5c12-9340-dd89866b1ca2
DOI
10.1101/2023.03.03.531059
Open publication

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Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destructionDOI 10.1101/2023.03.03.531059
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