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CD47 predominates over CD24 as a macrophage immune checkpoint in cancer

2024-11-26

Abstract excerpt

<h4>ABSTRACT</h4> Macrophages hold tremendous promise as effectors of cancer immunotherapy, but the best strategies to provoke these cells to attack tumors remain unknown. Here, we evaluated the therapeutic potential of targeting two distinct macrophage immune checkpoints: CD47 and CD24. We found that antibodies targeting these antigens could elicit maximal levels of phagocytosis when combined together in vitro....

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Identifiers and source

Literature Corpus work
191a4d3b-ae51-5b9a-a551-1177f10c6858
DOI
10.1101/2024.11.25.625185
Open publication

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CD47 predominates over CD24 as a macrophage immune checkpoint in cancerDOI 10.1101/2024.11.25.625185
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