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Article

Appraising familial prediction of proband outcomes in neurogenetic disorders

2026-05-22

Abstract excerpt

<h4>Background</h4> Gene dosage disorders impact cognition and psychopathology, but outcomes vary widely amongst carriers of the same variant. Recent work has sought to better predict proband outcomes using measures of corresponding traits in family members. However, family-based models have not yet been prospectively quantified across several traits in different genetic disorders, nor evaluated for the precision...

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Literature Corpus work
a2128a4e-b477-531b-af17-54485b5bb4d1
DOI
10.64898/2026.05.20.26353681
Open publication

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Appraising familial prediction of proband outcomes in neurogenetic disordersDOI 10.64898/2026.05.20.26353681
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