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Genetic Intelligence Project (GIP): A Probabilistic Framework for IQ Estimation Integrating Meta-GWAS, Replicated Loci, and Control Group Validation

2025-10-27

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<title>Abstract</title> <p>Human intelligence is a highly complex polygenic trait, with heritability estimated between 50% and 80% and modulated by environmental and epistatic factors. Genome-wide association studies (GWAS) have identified replicated loci of relevance to IQ, such as FOXO3, SNAP25, HMGA2, and SLC39A8, as well as functional variants in PDE1C and LINC01104. Additionally, the ADAM12 gene has emerged...

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Literature Corpus work
fd211c79-8cbe-555b-8fc0-f9c1795d0f1f
DOI
10.21203/rs.3.rs-7585469/v1
Open publication

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Genetic Intelligence Project (GIP): A Probabilistic Framework for IQ Estimation Integrating Meta-GWAS, Replicated Loci, and Control Group ValidationDOI 10.21203/rs.3.rs-7585469/v1
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