Article
Within-family influences on dimensional neurobehavioral traits in a high-risk genetic model.
Psychological medicine - 1 Oct 2022
Fiksinski Ania M, Heung Tracy, Corral Maria, Breetvelt Elemi J, Costain Gregory, Marshall Christian R, Kahn Rene S, Vorstman Jacob A S, Bassett Anne S
Abstract excerpt
BACKGROUND: Genotype-first and within-family studies can elucidate factors that contribute to psychiatric illness. Combining these approaches, we investigated the patterns of influence of parental scores, a high-impact variant, and schizophrenia on dimensional neurobehavioral phenotypes implicated in major psychiatric disorders. METHODS: We quantitatively assessed cognitive (FSIQ, VIQ, PIQ), social, and motor...
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