Article

Acquisition of discrete immune suppressive barriers contributes to the initiation and progression of preinvasive to invasive human lung cancer

2025-01-01

Abstract excerpt

Computerized chest tomography (CT)-guided screening in populations at risk for lung cancer has increased the detection of preinvasive subsolid nodules, which progress to solid invasive adenocarcinoma. Despite the clinical significance, there is a lack of effective therapies for intercepting the progression of preinvasive to invasive adenocarcinoma. To uncover determinants of early disease emergence and progression...

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Literature Corpus work: 8b62f2ed-d6fe-5c6c-9bc9-89cc51feeb36
DOI: 10.1101/2024.12.31.630523

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