Article

Single-cell RNA sequencing reveals route-specific remodeling of the tumor microenvironment and identifies predictive factors of breast cancer metastasis

2026-05-28

Abstract excerpt

<title>Abstract</title> <p>Breast cancer metastasis is the primary cause of patient mortality, driven by dynamic remodeling of the tumor microenvironment and the synergistic regulation of key factors. This study integrates single-cell transcriptomic data from 71,805 breast cancer cells, systematically mapping the dynamic evolution of tumor ecosystems across non-metastatic, lymph node-metastatic, and bone-metastat...

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Literature Corpus work: a56c1d1a-c877-5e1f-a743-1b1e61098065
DOI: 10.21203/rs.3.rs-9551458/v1

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