Article

Replicating RNA as a component of scrapie fibrils

2023-08-18

Abstract excerpt

Recently, electron cryo-microscopy (cryo-EM) maps of fibrils from the brains of mice and hamsters with five infectious scrapie strains have been published 1–5 and deposited in the electron microscopy data bank (EMDB) 6 . This represents long-awaited near-atomic level structural evidence, widely expected to confirm the protein-only prion hypothesis 7,8 . Instead, the maps reveal a second component, other than pr...

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Literature Corpus work: a1c6fdfb-c6fe-564c-92bf-9e4e432c2a38
DOI: 10.1101/2023.08.17.553578

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