Relationship of protease-resistant protein, scrapie-associated fibrils and tubulofilamentous particles to the agent of spongiform encephalopathies.

doi:10.1016/s0923-2516(06)80130-5

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Article

Relationship of protease-resistant protein, scrapie-associated fibrils and tubulofilamentous particles to the agent of spongiform encephalopathies.

Research in virology - 1 Jan 2000

Narang H K

Abstract excerpt

Tubulofilamentous particles and scrapie-associated fibrils (SAF) are ultrastructural markers, while protease-resistant protein (PrP) is a molecular biological marker for all spongiform encephalopathies. Review of all published work has suggested that PrP molecules aggregate to form a three-dimensional SAF. Further reports have suggested that a single-stranded DNA wraps round SAF and acquires an outer protein coat...

Topics

Amino Acid Sequence
Animals
Brain Chemistry
Cats
Cattle
Cricetinae
DNA, Single-Stranded
DNA, Viral
Endopeptidases
Humans
Membrane Glycoproteins
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Models, Biological

Molecular Sequence Data

Mutation

Nerve Tissue Proteins

PrP 27-30 Protein

Source

Open in PubMed

Identifiers

PMID: 1363618
DOI: 10.1016/s0923-2516(06)80130-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1363618-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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