Article
The nature of the scrapie agent: the virus theory.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) - 1 Jul 1996
Narang H
Abstract excerpt
All spongiform encephalopathies (SEs) are slow virus-transmissible infectious disorders of the brain. Tubulofilamentous particles/scrapie-associated fibrils (SAF) are ultrastructural markers, while protease-resistant protein (PrP) is a protein marker. The PrP molecules aggregate to form SAF, which occurs as an internal part of the tubulofilamentous particle termed nemavirus (NVP). Each NVP consists of three...
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