Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell transcriptomic profile of human pulmonary artery endothelial cells in health and pulmonary arterial hypertension

19 Jul 2021

Abstract excerpt

Pulmonary arterial hypertension (PAH) is an insidious disease characterized by severe remodeling of the pulmonary vasculature caused in part by pathologic changes of endothelial cell functions. Although heterogeneity of endothelial cells across various vascular beds is well known, the diversity among endothelial cells in the healthy pulmonary vascular bed and the pathologic diversity among pulmonary arterial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to MicroRNA in disease regulation
Share to Pulmonary Hypertension Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34282213
DOI: 10.1038/s41598-021-94163-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell transcriptomic profile of human pulmonary artery endothelial cells in health and pulmonary arterial hypertensionPMID 34282213Read ↗

Charting the cellular landscape of pulmonary arterial hypertension through single-cell omicsSemantic proximity Read ↗

Lung endothelial cell heterogeneity in health and pulmonary vascular diseaseSemantic proximity Read ↗

Multi-omics dissection of high TWAS-active endothelial pathogenesis in pulmonary arterial hypertension: bridging single-cell heterogeneity, machine learning-driven biomarkers, and developmental reprogramming.Semantic proximity Read ↗

Mapping disease-specific vascular cell populations responsible for obliterative arterial remodelling during the development of pulmonary arterial hypertension.Semantic proximity Read ↗

Single-cell characterization of the immune heterogeneity of pulmonary hypertension identifies novel targets for immunotherapySemantic proximity Read ↗

Emergence of disease-specific endothelial and stromal cell populations responsible for arterial remodeling during development of pulmonary arterial hypertensionSemantic proximity Read ↗

Assessing personalized molecular portraits underlying endothelial-to-mesenchymal transition within pulmonary arterial hypertensionSemantic proximity Read ↗

Endothelial Heterogeneity in Pulmonary Hypertension.Semantic proximity Read ↗

A <i>Tm4sf1</i> -Marked Subpopulation of Endothelial Stem/Progenitor Cells Identified by Lung Single-Cell Omics of Pulmonary Arterial HypertensionSemantic proximity Read ↗

Single-cell RNA sequencing profiling of mouse endothelial cells in response to pulmonary arterial hypertensionSemantic proximity Read ↗

Single-cell transcriptomics reveal diverging pathobiology and opportunities for precision targeting in scleroderma-associated versus idiopathic pulmonary arterial hypertensionSemantic proximity Read ↗

Single-cell transcriptomic analysis reveals distinct plasma cell populations in chronic thromboembolic pulmonary hypertension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.