Back to search

Article

AT2 Cell-Derived IgA Trapped by the Extracellular Matrix and Promoted Pulmonary Fibrosis

2023-05-03

Abstract excerpt

Pulmonary fibrosis is an interstitial lung disease caused by various factors such as exposure to workplace environmental contaminants, drugs, or X-rays. Epithelial cells are among the driving factors of pulmonary fibrosis. Immunoglobulin A (IgA), traditionally thought to be secreted by B cells, is an important immune factor involved in COVID-19 infection and vaccination. In current study, we found lung epithelial...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a16a2de3-b960-5267-9b8f-201090db0a54
DOI
10.2139/ssrn.4431410
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
AT2 Cell-Derived IgA Trapped by the Extracellular Matrix and Promoted Pulmonary FibrosisDOI 10.2139/ssrn.4431410
Immunoglobulin-producing AT2-like cells secrete IgA into the extracellular matrix in pulmonary fibrosisSemantic proximity
Immunoglobulin-producing AT2-like cells secrete IgA into the extracellular matrix in pulmonary fibrosisSemantic proximity
A spatial multi-omics atlas of the human lung reveals a novel gland-associated immune nicheSemantic proximity
A spatial multi-omics atlas of the human lung reveals a novel immune cell survival nicheSemantic proximity
Characterizing cellular heterogeneity in fibrotic hypersensitivity pneumonitis by single-cell transcriptional analysisSemantic proximity
IgG4 <sup>+</sup> plasma cell enrichment and λ-chain-biased BCR remodeling drive low-grade autoimmunity in chronic obstructive pulmonary diseaseSemantic proximity
T-cell Multiomic Analysis Identifies Subsets and Mechanisms of Interaction with Epithelial Cells in Idiopathic Pulmonary FibrosisSemantic proximity
Single-cell and spatial transcriptomics reveal a stress-induced EMT-like epithelial subset driving immune activation in silica-injured lungSemantic proximity
High-Throughput Analysis of Lung Immune Cells in a Murine Model of Rheumatoid Arthritis-Associated Lung DiseaseSemantic proximity
Single-Cell Profiling of Cells in the Lung of a Patient with Chronic Hypersensitivity Pneumonitis Reveals Inflammatory Niche with Abundant CD39+ T Cells with Functional ATPase Phenotype: A Case Study.Semantic proximity
Spatial multiomic profiling reveals distinct fibrotic epithelial niches in idiopathic pulmonary fibrosisSemantic proximity
Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosisSemantic proximity
Select a neighboring publication to make it the new centre.