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Article

Characterizing cellular heterogeneity in fibrotic hypersensitivity pneumonitis by single-cell transcriptional analysis

28 Jan 2022

Abstract excerpt

Abstract Fibrotic hypersensitivity pneumonitis (FHP) remains one of fatal interstitial pulmonary disease. Comprehensively dissecting the cellular heterogeneity of FHP paves the way for developing general gene therapeutic solutions for FHP. Here, utilizing an integrated strategy based on scRNA-seq, scTCR-seq, and bulk RNA-seq analysis of FHP profiles, we identified ten major cell types and 19 unique subtypes. FHP...

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Share to Extracellular vesicles in disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35091537
DOI: 10.1038/s41420-022-00831-x

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