Article

An immune-poised state of human bronchial epithelial cells mediates RSV resistance in adults

2026-02-03

Abstract excerpt

<h4>SUMMARY</h4> Respiratory syncytial virus (RSV) impairs STAT3 activation in infected ciliated cells in infants, but not adults, causing apoptosis to facilitate virus spread. How age regulates the STAT3 response to RSV in human bronchial epithelial cells (BEpiCs) is unknown. Here, we identify an age-associated immune-poised physiological state in human bronchial basal stem cells (BSCs) and progeny BEpiCs, rende...

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Literature Corpus work: a14b7c14-1946-5677-afa1-f4cd317f5f37
DOI: 10.64898/2026.02.02.703395

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