Article

Cell-intrinsic differences between human airway epithelial cells from children and adults

2020-04-20

Abstract excerpt

<h4>Summary</h4> The airway epithelium is a key protective barrier, the integrity of which is preserved by the self-renewal and differentiation of basal stem cells. Epithelial cells are central to the pathogenesis of multiple lung diseases. In chronic lung diseases, increasing age is a principle risk factor. Few studies have explored the differences between airway epithelial cells in children and adults and how t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 905e682a-0e9f-5ee4-a2a0-f5dd7bf48ea0
DOI: 10.1101/2020.04.20.027144

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cell-intrinsic differences between human airway epithelial cells from children and adultsDOI 10.1101/2020.04.20.027144Read

Cell-intrinsic differences between human airway epithelial cells from children and adultsSemantic proximity Read

Single-cell RNA sequencing reveals novel cell differentiation dynamics during human airway epithelium regenerationSemantic proximity Read

Culture Conditions Differentially Regulate the Inflammatory Niche and Cellular Phenotype of Tracheo-Bronchial Basal Stem CellsSemantic proximity Read

A single cell atlas of in vitro multi-systems uncovers in vivo lineage trajectory and cell state in the human lungSemantic proximity Read

A single-cell atlas of the human healthy airwaysSemantic proximity Read

Single-cell analysis of lung epithelial cells reveals age and cell population-specific responses to SARS-CoV-2 infection in ciliated cellsSemantic proximity Read

Transcriptional Regulation of Airway Epithelial Cell Differentiation: Insights into the Notch Pathway and BeyondSemantic proximity Read

Transcriptomic Analysis of Air–Liquid Interface Culture in Human Lung Organoids Reveals Regulators of Epithelial DifferentiationSemantic proximity Read

Cell Culture Differentiation and Proliferation Conditions Influence the In Vitro Regeneration of the Human Airway EpitheliumSemantic proximity Read

A single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lungSemantic proximity Read

A Single-Cell Atlas of the Human Healthy AirwaysSemantic proximity Read

A comparative study of in vitro air–liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolutionSemantic proximity Read