Article

Single-cell analysis of lung epithelial cells reveals age and cell population-specific responses to SARS-CoV-2 infection in ciliated cells

2024-04-02

Abstract excerpt

The ability of SARS-CoV-2 to evade antiviral immune signaling in the airway contributes to the severity of COVID-19 disease. Additionally, COVID-19 is influenced by age and has more severe presentations in older individuals. This raises questions about innate immune signaling as a function of lung development and age. Therefore, we investigated the transcriptome of different cell populations of the airway epitheli...

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Identifiers and source

Literature Corpus work: ceafe153-0ab4-5857-9755-2fac87b38514
DOI: 10.1101/2024.04.02.587663

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