Article

CCR9 overexpression promotes T-ALL progression by enhancing cholesterol biosynthesis

2023-05-24

Abstract excerpt

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy of the lymphoid progenitor cells contributing to ∼ 20% of the total ALL cases with higher prevalence in adults than the children. Despite the important role of human T-ALL cell lines in understanding the biology and treatment options, a detailed comparison of the tumorigenic potential of two commonly used T-ALL cell lines, MOLT4...

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Literature Corpus work: a1482b04-aac5-519f-8735-1d4de4451dcb
DOI: 10.1101/2023.05.24.542034

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