Article

In-Silico analysis of TAL1, TAL2 and LYL1 gene associated with T-ALL

2023-01-04

Abstract excerpt

<h4>Background: </h4> The primary tumours-specific TAL1 and TAL2 genes translocate to T-ALL. Precisely, the TAL2 (T-cell acute lymphocytic leukaemia 2) gene translocates to the chromosome breakpoint of t (7; 9) associated with the T-cell. The TAL2 genes transform in the TCR beta-chain identified in chromosome 7. TAL1 and TAL2 correspond to the LYL1 gene and represent a unique subgroup of bHLH TFs mediators of T-ce...

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Literature Corpus work: 628dbcf3-db9b-5ec3-9667-53c0acb40c01
DOI: 10.21203/rs.3.rs-2417874/v1

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