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[Research advance on the pathogenesis of T-ALL induced by notch 1 activating mutations].

Zhongguo shi yan xue ye xue za zhi - 1 Feb 2010

Xu Shuang-Nian, Chen Jie-Ping

Abstract excerpt

T-cell acute lymphoblastic leukemia (T-ALL) is the hematological malignancy of bone marrow characterized by the rapid proliferation and subsequent accumulation of immature T lymphocyte and mainly occurs in children and adolescents. In 1991, a kind of activating mutation of Notch 1 was found in a subset of T-ALL with chromosomal translocation t(7;9) for the first time. During the past 20 years since then,...

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PMID: 20137156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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