Article

Higher-order structures of the foot-and-mouth disease virus RNA-dependent RNA polymerase required for dynamic inter-molecular interactions involved in viral genome replication

2020-12-17

Abstract excerpt

Replication of many positive-sense RNA viruses occurs within intracellular membrane-associated compartments. These are believed to provide a favourable environment for replication to occur, concentrating essential viral structural and non-structural components, as well as protecting these components from host-cell pathogen recognition and innate immune responses. However, the details of the molecular interactions...

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Literature Corpus work: a12b1be4-b4d7-5ea9-949c-fbdbbe334169
DOI: 10.1101/2020.12.17.423260

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