Article

The Habenular Receptor GPR151 Regulates Addiction Vulnerability Across Drug Classes

2019-07-31

Abstract excerpt

<h4>SUMMARY</h4> The habenula controls the addictive properties of nicotine but also densely expresses opioid and cannabinoid receptors. As such, identification of strategies to manipulate habenular activity may yield new approaches to treat substance use disorders. Here we show that GPR151, an orphan G protein-coupled receptor (GPCR) highly enriched in the habenula of humans and rodents plays a critical role in...

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Literature Corpus work: a0f78194-ded0-5d89-8c71-f775963cc589
DOI: 10.1101/720508

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