Article
The genomic false shuffle: epigenetic maintenance of topological domains in the rearranged gibbon genome
2017-12-22
Abstract excerpt
The relationship between evolutionary genome remodeling and the three-dimensional structure of the genome remain largely unexplored. Here we use the heavily rearranged gibbon genome to examine how evolutionary chromosomal rearrangements impact genome-wide chromatin interactions, topologically associating domains (TADs), and their epigenetic landscape. We use high-resolution maps of gibbon-human breaks of synteny (...
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Identifiers and source
- Literature Corpus work
- a0e7a66e-ec8e-53db-8d02-fa54e120bc60
- DOI
- 10.1101/238360