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Incomplete lineage sorting of segmental duplications defines the human chromosome 2 fusion site early during African great ape speciation

2024-12-17

Abstract excerpt

<h4>ABSTRACT</h4> All great apes differ karyotypically from humans due to the fusion of chromosomes 2a and 2b, resulting in human chromosome 2. Yet, the structure, function, and evolutionary history of the genomic regions associated with this fusion remain poorly understood. Here, we analyze finished telomere-to-telomere chromosomes in great apes and macaques to show that the fusion was associated with multiple p...

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Literature Corpus work
15733ee2-899d-50ad-a96c-8b6426c12332
DOI
10.1101/2024.12.12.628057
Open publication

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Incomplete lineage sorting of segmental duplications defines the human chromosome 2 fusion site early during African great ape speciationDOI 10.1101/2024.12.12.628057
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