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The formation and propagation of human Robertsonian chromosomes

2024-09-26

Abstract excerpt

Robertsonian chromosomes are a type of variant chromosome found commonly in nature. Present in one in 800 humans, these chromosomes can underlie infertility, trisomies, and increased cancer incidence. Recognized cytogenetically for more than a century, their origins have remained mysterious. Recent advances in genomics allowed us to assemble three human Robertsonian chromosomes completely. We identify a common bre...

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Identifiers and source

Literature Corpus work
09eb0242-b33f-58b8-b8ed-49aa7c9c629b
DOI
10.1101/2024.09.24.614821
Open publication

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The formation and propagation of human Robertsonian chromosomesDOI 10.1101/2024.09.24.614821
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