Article

Single-cell RNA sequencing identifies progenitor dysfunction, inflammation and premature aging in ex vivo airway epithelium-derived from transplant recipients

2025-12-26

Abstract excerpt

Pulmonary dysfunction is a common complication following hematopoietic stem cell transplantation (HSCT) or lung transplantation (LT). Bronchiolitis obliterans syndrome (BOS), an alloimmune complication of transplantation, with complex pathophysiology, contributes substantially to morbidity and mortality in these settings. We aimed to identify common epithelial features predisposing to BOS by comparing epithelia fr...

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Literature Corpus work: a0dda1b8-68dd-594c-9662-e7a4cce49445
DOI: 10.64898/2025.12.26.696372

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