Article

Alveolar epithelial cell plasticity and injury memory in human pulmonary fibrosis

2025-06-10

Abstract excerpt

Acute and repetitive lung epithelial injury can lead to irreversible and even progressive pulmonary fibrosis; Idiopathic pulmonary fibrosis (IPF) is a fatal disease and quintessential example of this phenomenon. The composition of epithelial cells in human pulmonary fibrosis – irrespective of disease etiology – is marked by the presence of Aberrant Basaloid cells: an abnormal cell phenotype with pro-fibrotic and s...

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Literature Corpus work: 30c52e28-7d86-52f0-b47f-29cc36579445
DOI: 10.1101/2025.06.10.658504

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