Article

Distinct fibrotic, epithelial and immune transcriptomic programs in phenotypes of chronic lung allograft dysfunction

2026-05-28

Abstract excerpt

<h4>Background</h4> Chronic lung allograft dysfunction (CLAD) is the major cause of late mortality after lung transplantation and includes two principal phenotypes, bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS). RAS and other phenotypes with RAS-like opacities (RLO) on chest imaging have a poorer prognosis. Despite clear clinical and pathological differences, molecular distincti...

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Literature Corpus work: da9d8752-f702-5bb7-b54c-0e7e305c67b7
DOI: 10.64898/2026.05.24.727536

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