Article

Entropy sorting of single cell RNA sequencing data reveals the inner cell mass in the human pre-implantation embryo

2022-04-10

Abstract excerpt

<h4>ABSTRACT</h4> A major challenge in single cell gene expression analysis is to discern meaningful cellular heterogeneity from technical or biological noise. To address this challenge, we present Entropy Sorting, a mathematical framework that distinguishes genes indicative of cell identity. ES achieves this in an unsupervised manner by quantifying if observed correlations between features are more likely to hav...

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Literature Corpus work: 82b314f5-b9a1-5622-b468-9f42db1c7821
DOI: 10.1101/2022.04.08.487653

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