Article

An Integrated muti-omics cell atlas of the human trabecular meshwork and ciliary body

2026-06-22

Abstract excerpt

The trabecular meshwork (TM) and ciliary body (CB) regulate aqueous humor dynamics and intraocular pressure (IOP), and TM/Schlemm’s canal (SC) dysfunction underlies glaucoma. Here, we present a spatially resolved multi-omics atlas of human TM and CB, integrating snRNA-seq, scRNA-seq, and snATAC-seq from over one million cells and nuclei across 112 donors with Xenium spatial transcriptomics. We identified 9 major c...

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Literature Corpus work: 00463287-f3b4-5ff6-816e-a4cb43c003df
DOI: 10.64898/2026.06.17.732980

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