Article

Treatment of Acute Kidney Injury Using a Dual Enzyme Embedded Metal-organic Framework-mediated Cascade That Catalyzes in Vivo ROS Scavenging

2021-05-18

Abstract excerpt

<h4>Background: </h4> Significant advances have been made in recent years to utilize natural enzymes with antioxidant properties for the treatment of acute kidney injury (AKI). However, these enzymes have limited clinical utility due to their limited cellular uptake, poor pharmacokinetic properties, and suboptimal stability. We prepared a novel biomimetic mineralization approach to overcome these limitations. <h4>...

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Literature Corpus work: a0553e5b-c588-5c69-ba68-ba2cded076a9
DOI: 10.21203/rs.3.rs-502119/v1

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Treatment of Acute Kidney Injury Using a Dual Enzyme Embedded Metal-organic Framework-mediated Cascade That Catalyzes in Vivo ROS ScavengingDOI 10.21203/rs.3.rs-502119/v1Read

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