Article

Protective Effect of Platinum Nano-antioxidant and Nitric Oxide Against Hepatic Ischemia-Reperfusion Injury

2021-07-13

Abstract excerpt

<title>Abstract</title> <p>Specific therapeutic interventions of hepatic ischemia-reperfusion injury (IRI) to attenuate liver dysfunction or multiple organ failure following liver surgery and transplantation remain a key concern. Here we present an innovative strategy by integrating a platinum nanoantioxidant and nitric oxide synthase (iNOS) into the zeolitic imidazolate framework-8 (ZIF-8)-based hybrid nanoreact...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 30491e29-eea7-53e9-815d-3d090d0c952f
DOI: 10.21203/rs.3.rs-660251/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Protective Effect of Platinum Nano-antioxidant and Nitric Oxide Against Hepatic Ischemia-Reperfusion InjuryDOI 10.21203/rs.3.rs-660251/v1Read

Tumor Microenvironment-Responsive CA@ZIF-8/MnO 2 Nanoreactor for Self-Reinforcing Cascade Chemodynamic Therapy and ImmunomodulationSemantic proximity Read

Tregs Biomimetic Nanoparticle to Reprogram Inflammatory and Redox Microenvironment in Infarct Tissue to Inhibit the Remodeling of the Left Ventricle of Myocardial Ischemia Reperfusion Injury in MiceSemantic proximity Read

Treatment of Acute Kidney Injury Using a Dual Enzyme Embedded Metal-organic Framework-mediated Cascade That Catalyzes in Vivo ROS ScavengingSemantic proximity Read

Repair spinal cord injury with a versatile anti-oxidant and neural regenerative nanoplatformSemantic proximity Read

A super-assembled synergistically nanoplatform AP@ZIF-8 Pt for hepatocarcinoma therapySemantic proximity Read

A ZnO@ZIF-8/Ag Dual-Platform Nanocomposite Synergizing ROS Generation for Bactericidal-Immunomodulatory Wound TherapySemantic proximity Read

Restoration of dysregulated intestinal barrier and inflammatory regulation through synergistically ameliorating hypoxia and scavenging reactive oxygen species using ceria nanozymes in ulcerative colitisSemantic proximity Read

Hypoxia-Responsive Nanoreactors to Amplify Oxidative Damage Through Multiple Cascaded Pathways for Promoting Photodynamic/Ferroptosis-Induced ROS Generation and Simultaneously Disrupting Tumor Antioxidant Defense SystemSemantic proximity Read

Zinc Oxide and Titanium Dioxide Nanoparticles Bio fabricated for Enhanced Antimicrobic, Antioxidant, and Antitumor PerformanceSemantic proximity Read

ZnO nanomaterials target mitochondrial apoptosis and mitochondrial autophagy pathways in cancer cellsSemantic proximity Read

Self-Detoxifying Nanocatalytic Medicine CaO2@Cu-BAL for Enhanced Chemodynamic Therapy of TumorSemantic proximity Read

A CDDP-Cross-Linked Nanoprodrug for Combination Therapy Based on Dual-Augmented Cascade ReactionsSemantic proximity Read