Article

Ammonium Tetrathiomolybdate Relieves Oxidative Stress in Cisplatin-induced Acute Kidney Injury via NRF2 Signaling Pathway

2023-02-08

Abstract excerpt

<title>Abstract</title> <p>Cisplatin is an efficient chemotherapeutic agent for various solid tumors, but its usage is restricted by nephrotoxicity. A single dose of cisplatin can cause acute kidney injury (AKI), which is characterized by rapid reduction in kidney function. However, the efficacy of current therapies, such as hydration, is limited. It is vital to develop novel therapeutic reagents that have antica...

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Literature Corpus work: 7bf75c8f-9311-5b13-b46b-3063995dd5b6
DOI: 10.21203/rs.3.rs-2523088/v1

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