Article

Zinc oxide nanoparticles induce renal injury by initiating oxidative stress, mitochondrial damage and apoptosis in renal tubular epithelial cells

2023-03-14

Abstract excerpt

<title>Abstract</title><p>Zinc oxide nanoparticles (ZnO NPs) are widely used in many fields due to their unique physicochemical properties. However, the renal toxicity of ZnO NPs and the underlying mechanisms has not been well elucidated. Here we found that ZnO NPs induced injury of human renal proximal tubular epithelial cells (HK-2) in a dose- and size-dependent manner, as revealed by CCK-8, LDH and AnnexinV-FIT...

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Literature Corpus work: 754e6e3b-ff9d-5fca-b036-0e59ac3057c6
DOI: 10.21203/rs.3.rs-2664676/v1

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