Article

Midbrain Dopaminergic Neuron Development is Regulated by Two Molecularly Distinct Subtypes of Radial Glia Cells

2024-03-08

Abstract excerpt

Understanding midbrain dopaminergic (mDA) neuron development is key to advancing cell replacement therapies for Parkinson’s disease (PD). Recent single-cell RNA-sequencing (scRNA-seq) studies have identified different subtypes of transient radial glia (Rgl) cell types in the developing mouse and human ventral midbrain. However, their individual functions and their impact on mDA neuron development are unclear. Here...

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Literature Corpus work: a0240d78-967a-5e6f-b5ff-ad31512c8d55
DOI: 10.1101/2024.03.08.584031

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