Article

YAP and collagen remodelling support cell proliferation and tumour aggressiveness in uterine leiomyosarcoma

2022-06-29

Abstract excerpt

Fibrillar collagen deposition, stiffness, and downstream signalling support the development of leiomyomas (LM), common benign mesenchymal tumours of the uterus, and are associated with aggressiveness in multiple carcinomas. Compared to epithelial carcinomas, however, the impact of fibrillar collagens on malignant mesenchymal tumours, including uterine leiomyosarcoma (LMS), remains elusive. In this study, we analys...

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Literature Corpus work: 9fdef0cc-7faa-53b6-b9b1-92d21b20ba40
DOI: 10.1101/2022.06.27.497746

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