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The role of network‐forming collagens in cancer progression

24 Mar 2022

Abstract excerpt

Collagens are the main components of extracellular matrix in the tumor microenvironment. Both fibrillar and nonfibrillar collagens are involved in tumor progression. The nonfibrillar network-forming collagens such as type IV and type VIII collagens are frequently overexpressed in various types of human cancers, which promotes tumor cell proliferation, adhesion, invasion, metastasis and angiogenesis. Studies on...

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PMID: 35322886
DOI: 10.1002/ijc.34004

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